Wenping Wang Positioning Drug Candidates in a Competitive Landscape - an integrated, data-driven approach
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ME de Jonge(1), ADR Huitema(1), AC Tukker (2), SM van Dam(1), S Rodenhuis(2), JH Beijnen(1,2). Prospective Bayesian pharmacokinetically guided dosing of cyclophosphamide, thiotepa and carboplatin in high-dose chemotherapy.
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Dinesh de Alwis1, Sophie Callies1, James Wright2, Leon Aarons3 and Micheal Burgess1 Resisting population PK, the story of P-gp inhibition and co-administered chemotherapy.
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Pedro Berraondo1, Gloria González-Aseguinolaza1, Iñaki F. Trocóniz2 Application of Pharmacokinetic/Pharmacodynamic Concepts to Modeling in Gene Therapy
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A.S. Zandvliet(1), S. Yasuda(2), W. Copalu(3), J.H.M. Schellens(4,5), J.H. Beijnen(1,5), A.D.R. Huitema(1) A physiologically based population pharmacokinetic model describing the non-linear disposition and blood distribution of indisulam in Caucasian and Japanese patients
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Mick Looby and Amy Racine An approach to formal decision making in exploratory development
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Lena E Friberg(1), Geoffrey K Isbister(2), L Peter Hackett(3) and Stephen B Duffull(1) Pharmacokinetic-Pharmacodynamic Modelling of QT-Prolongation following Deliberate Self-Poisonings with Citalopram
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S. Glatt(1), C Pitou (1), J. Yingling (1), L. Bueno (2), D. de Alwis (1), I.F Troconiz (2) Preclinical Population PK/PD of TGF beta RI Kinase inhibitor for Cancer
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Alan Maloney(1), Klaas Zuideveld(2), Karin Jorga(2), Cornelia Weber(2), Nicolas Frey(2), Per Olsson(1), Eric Snoeck(1) An Application of Modelling and Simulation to Type 2 Diabetes: Development of a general drug-disease model based on a meta analysis of over 40 studies investigating 5 PPAR drugs
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Donald R. Stanski, MD Model-Based Drug Development: A FDA Critical Path Opportunity
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José Pinheiro(1), Chyi-Hung Hsu(1), and Fei Chen(2) Analyzing Event History Data with nlme in S
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France Mentré History and new developments in estimation methods in nonlinear mixed-effects models
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Pascal Girard and France Mentré A comparison of estimation methods in nonlinear mixed effects models using a blind analysis
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Adrian Dunne Introduction to Categorical Data Analysis
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Nick Holford PKPD Workshop 'An overview on how to use NONMEM for PKPD analyses'
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